May 28, 2025 | Black & Kletz Allergy
Histamine is a biogenic amine (i.e., an organic compound made up of carbon and nitrogen bonds) with several biological effects across different types of cells, mediated through the activation of histamine receptors. Histamine is normally present within mast cells and other similar cell types such as basophils. Mast cells are cells of the connective tissue that contain many granules rich in histamine and other chemicals. Histamine is also present in various […]
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May 23, 2025 | Black & Kletz Allergy
Individuals with pollen allergies may be affected throughout the year, depending on where they live or travel. In the Washington, DC, Northern Virginia, and Maryland metropolitan area, pollen allergies are bothersome to allergic individuals generally from late February through the first frost, which is usually at the end of October. In this region, trees are the […]
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April 15, 2025 | Black & Kletz Allergy
There are a few over-the-counter (OTC) medications that some patients with asthma and other respiratory conditions occasionally use. One of them is an inhaler called Primatene Mist. Primatene Mist contains epinephrine (i.e., adrenaline) in an inhalable form. Though it is the same drug that is in an EpiPen, Auvi-Q, Adrenaclick, and other self-injectable epinephrine devices […]
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April 10, 2025 | Black & Kletz Allergy
Pollen food allergy syndrome (PFAS), also known as oral allergy syndrome, is a condition in which there is first a “sensitization” of the immune system to various pollens and subsequent “reactions” when exposed to these pollens. Secondly, there is a similarity of the protein allergens in the pollen and the protein allergens of certain raw or […]
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March 25, 2025 | Black & Kletz Allergy
Spring is here! This means that quite a few Washingtonians will be pretty miserable as they will be suffering from hay fever (i.e., allergic rhinitis). In the early Spring, tree pollen is mostly to blame for the annoying symptoms that cause hay fever. Other than tree pollen, molds are also a common environmental allergen that plays havoc with allergy […]
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March 20, 2025 | Black & Kletz Allergy
Food protein-induced enterocolitis syndrome (FPIES) is a rare condition that causes gastrointestinal symptoms several hours after consumption of certain foods by an individual who has an intolerance to that food. The prevalence rate in the United States is approximately 0.5%. The most common types of food allergy in children and adults are mediated by an […]
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February 13, 2025 | Black & Kletz Allergy
Some individuals have episodes of swelling or “angioedema” of various tissues that may occur without any known rhyme or reason. They may have 1 episode or they may have multiple or recurrent episodes. Most people with this condition are very surprised and nervous when they notice an area of their body swelling up right in […]
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February 11, 2025 | Black & Kletz Allergy
Four viral infections are surging in the country this year. Three of them are respiratory viruses and one is a gastrointestinal infection. Influenza (“flu”) usually tends to peak in the Winter. The Centers for Disease Control’s (CDC) statistics reveal that more than 30% of the lab tests were positive for the flu in January of […]
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January 16, 2025 | Black & Kletz Allergy
Hives, also known as urticaria, is a very bothersome problem for those affected. They are usually quite itchy although they do not have to be. A hive is typically a raised welt, wheal, or bump on the skin that may have an accompanying red blotch surrounding the bump. Hives however can be flush with the […]
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January 09, 2025 | Black & Kletz Allergy
An eosinophil is a type of white blood cell that has a role in fighting against parasitic infections and responding to allergens. Eosinophils normally constitute about 5 to 8% of the white blood cells in one’s bloodstream. Their absolute numbers range from 100 to 500 eosinophils per microliter of blood. In individuals who are atopic, (i.e., people […]
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